Highmark Stadium will play host to Monday's Round 15 NFL game between Carolina Panthers and Buffalo Bills. The game kicks off at 5:01 am with Buffalo Bills heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Carolina Panthers vs. Buffalo Bills game and give you our free tips and bets.

When: Monday December 20, 2021 at 5:01 am

Where: Highmark Stadium

Bet 💰: Bet On This Match HERE

Carolina Panthers vs Buffalo Bills Odds

Carolina Panthers vs Buffalo Bills Preview

Another team in desperate need of a palate cleansing performance is a Buffalo side who just could not get things to go their way in the last two weeks.

The good news is that Carolina does not have Bill Belichick or Tom Brady to deal with and the Panthers are well and truly overmatched here.

Had Buffalo not produced that second half rally it might have been worth taking the Panthers at the line, but the Bills showed there is still some fight in them.

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Carolina Panthers vs Buffalo Bills Tip