SoFi Stadium will play host to Monday's Round 18 NFL game between San Francisco 49ers and Los Angeles Rams. The game kicks off at 8:26 am with Los Angeles Rams heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Los Angeles Rams game and give you our free tips and bets.

When: Monday January 10, 2022 at 8:26 am

Where: SoFi Stadium

Bet 💰: Bet On This Match HERE

San Francisco 49ers vs Los Angeles Rams Odds

San Francisco 49ers vs Los Angeles Rams Preview

In a busy slate of games kicking off at 8:25 (AEDT), this is the one you will want to pay the most attention to.

Both teams have plenty to play for and will have two other games paying attention to how this will unfold.

LA is riding a five game winning streak and has shown an ability to get wins even when they are not playing near their best.

The play of both quarterbacks is a huge concern with Matthew Stafford committing turnovers at an alarming rate and either an injured Jimmy Garoppolo or an inexperienced Trey Lance starting for the 49ers.

When you compare the two, the Rams have the better equipped roster to cover for their struggling quarterback and it seems likely that whoever starts for San Francisco will be running for their life from the Rams pass rush.

I’ll back their difference makers to get them over the line and claim the NFC West title.

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San Francisco 49ers vs Los Angeles Rams Tip