State Farm Stadium will play host to Sunday's Round 16 NFL game between San Francisco 49ers and Arizona Cardinals. The game kicks off at 8:30 am with Arizona Cardinals heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Arizona Cardinals game and give you our free tips and bets.

When: Sunday December 27, 2020 at 8:30 am

Where: State Farm Stadium

Bet 💰: Bet On This Match HERE

San Francisco 49ers vs Arizona Cardinals Odds

San Francisco 49ers vs Arizona Cardinals Preview

For the third time in four weeks, the 49ers head to State Farm Stadium in Arizona, except this time they will be the visitors as they take on the stadium’s regular tenants.

The Cardinals playoff push began with a 24-20 upset in Week 1 as Kyler Murray ran for 91 yards and a score.

Last week he had his best day of the season through the air going for over 400 yards and three touchdowns in their win over the Eagles.

It looks like he has shaken off that shoulder injury that limited him for a while earlier in the month and is looking like the one time MVP candidate.

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San Francisco 49ers vs Arizona Cardinals Tip