Gillette Stadium will play host to Monday's Round 16 NFL game between Buffalo Bills and New England Patriots. The game kicks off at 5:01 am with New England Patriots heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Buffalo Bills vs. New England Patriots game and give you our free tips and bets.

When: Monday December 27, 2021 at 5:01 am

Where: Gillette Stadium

Bet 💰: Bet On This Match HERE

Buffalo Bills vs New England Patriots Odds

Buffalo Bills vs New England Patriots Preview

Three weeks after their wild and windy clash in Buffalo on Monday Night Football, New England and Buffalo will reunite at Gillette Stadium for the rematch that could decide the AFC East.

Based on the current weather forecast for Foxborough, the conditions should be a little bit more palatable for all involved this weekend.

The Patriots took that first game on the back of a punishing ground game that took over the game and allowed them to control the clock from start to finish.

While New England is likely to throw more than three passes in this game, it would be surprising for them to abandon their run first approach considering how vulnerable the Bills have been up front.

This might be the toughest game to pick of the weekend and in a situation like this, you have to back the coaching edge, which goes to Bill Belichick.

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Buffalo Bills vs New England Patriots Tip