Daria Gavrilova has lost to Simona Halep in the second round of the WTA event in Montreal.
World No.5 Halep beat the Australian 6-2 6-3 on Tuesday (Wednesday AEST).
Earlier, Canadian Eugenie Bouchard defeated Lucie Safarova 6-3 3-6 7-6.
Bouchard came back from a 3-1 deficit in the tiebreaker with six straight points, securing victory on Safarova’s 10th double-fault of the match.
World No.42 Bouchard will next face the winner of a match between Dominika Cibulkova and Mariana Duque-Marino.
It did not go so well for Aleksandra Wozniak, another local favorite, who lost 6-4 7-6 (4) to Sara Errani of Italy.
Errani’s next opponent is 14th-seeded Karolina Pliskova, who got past Kateryna Bondarenko 3-6 6-2 7-5.
A match-up of the Madisons looms as 10th-seeded Madison Keys breezed by Elena Visnina 6-4 6-0 and will face fellow American Madison Brengle in the second round.
Lucky loser Christina McHale of the US posted a 6-4 3-0 win over qualifier Shuai Zhang, who retired in the second set.
McHale will next face 16th-seeded Anastasia Pavlyuchenkova, who defeated Yulia Putintseva 6-4 1-6 7-5.
Andrea Petkovic of Germany downed Alize Cornet of France 7-6 (1) 6-3 to advance to a second-round meeting with 12th-seeded Petra Kvitova.
Daria Kasatkina beat Misaki Doi 3-6 6-3 6-1 and will face 13th-seeded Samantha Stosur, while Monica Niculescu beat Jelena Ostapenko 3-6 7-5 6-1 to advance against fourth-seeded Agnieszka Radwanska.
French Open champion and third-seeded Garbine Muguruza withdrew with a digestive illness in another setback for the women’s draw.