Tennis titans Novak Djokovic and Roger Federer have set up a blockbuster US Open final with commanding semi-final victories in New York.

Djokovic crushed defending champion Marin Cilic 6-0 6-1 6-2 in the most one-sided US Open semi-final in professional tennis history before Federer continued his near-flawless campaign with a 6-4 6-3 6-1 rout of Swiss countryman Stan Wawrinka.

Looking to add a second title to his 2011 crown, the top-ranked Djokovic needed just one hour and 25 minutes to see off ninth-seeded Cilic to progress to his fourth grand slam final in a season for the first time.