A shoulder injury has ruled England scrum-half Ben Youngs out of the third and final Test against series winners South Africa in Port Elizabeth on Saturday.
The Leicester Tigers halfback starred in the 36-27 second Test defeat in Johannesburg this weekend, scoring two opportunist second half tries to spark a brave comeback.
Although England have a game against the Northern Barbarians in Potchefstroom on Tuesday, coach Stuart Lancaster was sure to rest Youngs ahead of the Test with the tourists trying to avoid a whitewash after also losing the first in Durban.
Harlequins Karl Dickson is expected to arrive in South Africa on Monday as a replacement and could face the Baa Baas, a team composed of northern-based players from the second tier of the Currie Cup.
That would leave Lee Dickson and Danny Care to fight for the No.9 shirt against the Springboks, who have won their last nine clashes with England, including the 2007 World Cup final in Paris.