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Penrith Panthers vs North Queensland Cowboys Odds, Teams and Betting Tips – NRL 2025

CommBank Stadium will play host to Friday's Round 5 NRL game between Penrith Panthers and North Queensland Cowboys. The game kicks off at 6:00 pm with Penrith Panthers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Penrith Panthers vs. North Queensland Cowboys game and give you our free tips and bets.

When: Friday April 4, 2025 at 6:00 pm

Where: CommBank Stadium

Bet: Bet On This Match HERE

Penrith Panthers vs North Queensland Cowboys Odds

Penrith Panthers vs North Queensland Cowboys Preview

The Penrith Panthers will aim to break their three-game losing streak when they face the North Queensland Cowboys at CommBank Stadium on Friday evening. This slump, their longest since 2019, has left them in unfamiliar territory, sitting 13th on the ladder. Concerns over their form grew last week after trailing 28-0 against Souths before a late resurgence.

Meanwhile, the Cowboys enter the clash with confidence after securing their first win of 2025—a 30-20 victory over the Raiders at home. Penrith will be boosted by the return of star halfback Nathan Cleary from concussion, but they’ll be without Origin winger Brian To’o (hamstring), who is sidelined for a month, with Casey McLean taking his place. Scott Sorensen also remains out due to concussion.

The Cowboys, looking to build momentum, will field the same lineup that delivered last week’s win.

Penrith Panthers vs North Queensland Cowboys Tip

Penrith Panthers
$1.22
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We're tipping Penrith Panthers to win at $1.22 odds.

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