Gold Coast captain Nate Myles has been ruled out of Sunday’s NRL clash with St George Illawarra.

The Queensland and Australian representative will miss his final home game with the Titans due to a thumb injury.

Myles’ omission has forced a big reshuffle by coach Neil Henry.

Brad Tighe has been included in the line-up at centre, with Nene McDonald moving to the wing and Kalifa Faifai Loa shifting to the bench.

Prop Eddy Pettybourne comes off the bench to replace Myles in the starting line-up, while hooker Beau Falloon will captain the Titans for what is also his final home game at the club.

The Dragons have gone with an unchanged line-up.