Raymond James Stadium will play host to Monday's Round 6 NFL game between Tampa Bay Buccaneers and San Francisco 49ers. The game kicks off at 4:00 am with Tampa Bay Buccaneers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Tampa Bay Buccaneers vs. San Francisco 49ers game and give you our free tips and bets.
When: Monday October 13, 2025 at 4:00 am
Where: Raymond James Stadium
Bet: Bet On This Match HERE
Tampa Bay Buccaneers vs San Francisco 49ers Odds
Tampa Bay Buccaneers vs San Francisco 49ers Preview
Tampa Bay might not be the best team in the NFC, but they are close to it and definitely the most entertaining team to watch at the moment.
Baker Mayfield is making a case to be the NFL MVP and he might be the value play in that market at $13.
Im all in on the Bucs going forward with the way they just keep finding ways to pull out games.
San Francisco did have a good win over the Rams last week, but they tend to play those guys very well and look set to come crashing back to earth here.
Give me Tampa with Mayfield leading the way.
Content provided by Ladbrokes
Head To Head Bet
We're tipping Tampa Bay Buccaneers to win at $1.60 odds.