Levi's Stadium will play host to Monday's Round 10 NFL game between San Francisco 49ers and Los Angeles Rams. The game kicks off at 8:25 am with Los Angeles Rams heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Los Angeles Rams game and give you our free tips and bets.
When: Monday November 10, 2025 at 8:25 am
Where: Levi's Stadium
Bet 💰: Bet On This Match HERE
San Francisco 49ers vs Los Angeles Rams Odds
San Francisco 49ers vs Los Angeles Rams Preview
Itll be tough to match the hype of Bills-Chiefs last week but this is going to have as much of an impact on the NFC playoff field as that blockbuster last week.
Weve got two really good teams facing off at the site of Februarys Super Bowl and with the winner could take control of the division.
San Francisco stunned LA back in Week 5 with an overtime victory but the Rams left a lot on the table in that game and I like their chances of bouncing back.
Especially with Matt Stafford in the form he is in right now, suddenly looking like an MVP candidate.
Content provided by Ladbrokes
Head To Head Bet
We're tipping Los Angeles Rams to win at $1.45 odds.
