Levi’s Stadium will play host to Monday's NFL game between San Francisco 49ers and Detroit Lions. The game kicks off at 9:40 am with San Francisco 49ers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Detroit Lions game and give you our free tips and bets.

When: Monday January 29, 2024 at 9:40 am

Where: Levi’s Stadium

Bet 💰: Bet On This Match HERE

San Francisco 49ers vs Detroit Lions Odds

San Francisco 49ers vs Detroit Lions Preview

If Detroit is going to advance to the Super Bowl for the first time in franchise history, they are going to have to do it the hard way as they take on the San Francisco 49ers in Santa Clara.

Kyle Shanahan’s team has been the one of, if not the consensus best teams in the league all season and plenty of players on this roster were part of the team that fell at the final hurdle in the 2019 season.

They are in the final four for the fourth time in five seasons and head into this game as justifiable short priced favourites.

But the story of the Lions, combined with the fact they have the pieces to cause the 49ers problems means there is a case for the upset.

Detroit’s quick strike offence means they can get out to an early lead and negate the ground game of San Francisco, while freeing up Aidan Hutchinson and company to get after Brock Purdy when he drops back to pass.

All of that is great in theory but the chances of it playing out perfectly for Detroit are slim to none, even with San Francisco potentially playing without Deebo Samuel.

They still have Christian McCaffrey to get the ball to and with a week to prepare, Shanahan will be able to find ways to utilise George Kittle and Brandon Aiyuk a bit more effectively.

Combine that with the likes of Fred Warner and Dre Greenlaw on defence and the 49ers just seem like they are going to have too much talent to lose this game.

While the fun part of the story would see the Lions win and advance on to Las Vegas in a fortnight, the far more likely scenario is the stage gets the better of them and they get their doors blown off.

McCaffrey is key to the 49ers success and there is value to be had backing him for one of those all-time performances, the less San Francisco needs Purdy to do the better and their best path to victory is getting the ball in the hands of their best player.

As for other value bets two touchdown scorers leap off the page, starting with Detroit’s rookie tight end Sam LaPorta, while San Francisco’s opportunistic defence is a great chance of taking one back to the house if they have the opportunity.

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San Francisco 49ers vs Detroit Lions Tip