Acrisure Stadium will play host to Monday's Round 13 NFL game between Pittsburgh Steelers and Buffalo Bills. The game kicks off at 8:25 am with Buffalo Bills heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Pittsburgh Steelers vs. Buffalo Bills game and give you our free tips and bets.

When: Monday December 1, 2025 at 8:25 am

Where: Acrisure Stadium

Bet 💰: Bet On This Match HERE

Pittsburgh Steelers vs Buffalo Bills Odds

Pittsburgh Steelers vs Buffalo Bills Preview

The Pittsburgh Steelers enter this battle looking to lean on their trademark toughness and defensive grit. Their pass rush and physical secondary will aim to disrupt Buffalo’s rhythm early, forcing the Bills into tight-window throws. Offensively, Pittsburgh will look to establish balance, mixing controlled passes with timely runs to keep drives alive.

The Buffalo Bills counter with a high-powered, fast-moving offense built around dynamic quarterback play and versatile weapons. Their ability to stretch the field vertically and attack in space will challenge Pittsburgh’s defense throughout the game. On the other side, Buffalo’s defense will focus on creating pressure and limiting the Steelers’ chances for sustained momentum.

This matchup promises a clash of intensity and contrasting styles. Pittsburgh thrives in grinding, defensive-heavy contests, while Buffalo looks to open the game up with explosive drives and quick scoring. With both teams fighting for rhythm and playoff positioning, this showdown is set to deliver big moments, physical play, and a dramatic finish.