Caesars Superdome will play host to Monday's Round 1 NFL game between New Orleans Saints and Arizona Cardinals. The game kicks off at 3:00 am with Arizona Cardinals heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the New Orleans Saints vs. Arizona Cardinals game and give you our free tips and bets.
When: Monday September 8, 2025 at 3:00 am
Where: Caesars Superdome
Bet: Bet On This Match HERE
New Orleans Saints vs Arizona Cardinals Odds
New Orleans Saints vs Arizona Cardinals Preview
There will be a common theme among New Orleans game previews this season with the Saints expected to be one of if not the worst team in the NFL.
It really doesnt matter who is starting at quarterback for the home team here, none of their options are going to inspire a whole lot of confidence, frankly theyd be lucky to score 10 points.
Arizona has to be thanking their lucky stars that this is their Week 1 opponent as it affords them a chance to start their season on the perfect note.
Knowing how important a playoff appearance is for this team, the Cardinals should take full advantage of an overmatched opponent and enjoy the opportunity to run roughshod over the Saints in the Superdome.
Although it might not quite be the blowout the Super Bowl was in this venue back in February.
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Head To Head Bet
We're tipping Arizona Cardinals to win at $1.32 odds.