New England Patriots vs Buffalo Bills Tips, Odds & Predictions – NFL 2025

Gillette Stadium will play host to Monday's Round 15 NFL game between New England Patriots and Buffalo Bills. The game kicks off at 5:00 am with Buffalo Bills heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the New England Patriots vs. Buffalo Bills game and give you our free tips and bets.

When: Monday December 15, 2025 at 5:00 am

Where: Gillette Stadium

Bet 💰: Bet On This Match HERE

New England Patriots vs Buffalo Bills Odds

New England Patriots vs Buffalo Bills Preview

The Bills look like they have wasted an era with the Patriots now looking like a new young side ready to control the AFC East.

Or will this week be their moment to stumble as we get closer to business end of the season?

Patriots are 11-2 and sitting at the 2 seed – Drake Maye has been sensational.

Bills are 9-4 after that thriller against the Bengals 39-34 but probably can’t catch New England in the division so its just a matter of who makes their statement.

Bills are still hard to trust. I’ll take Pats.

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Head To Head Bet

Buffalo Bills
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We're tipping Buffalo Bills to win at $1.87 odds.

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