SoFi Stadium will play host to Friday's Round 1 NFL game between Los Angeles Rams and Buffalo Bills. The game kicks off at 10:20 am with Buffalo Bills heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Los Angeles Rams vs. Buffalo Bills game and give you our free tips and bets.

When: Friday September 9, 2022 at 10:20 am

Where: SoFi Stadium

Bet 💰: Bet On This Match HERE

Los Angeles Rams vs Buffalo Bills Odds

Los Angeles Rams vs Buffalo Bills Preview

As has become tradition, the reigning Super Bowl champions will open the NFL season, with the Los Angeles Rams hosting current Super Bowl LVII favourites, the Buffalo Bills. After losing the most exciting game of the 2021 season in the AFC Divisional Round, the Bills offset the loss of offensive coordinator Brian Daboll by acquiring star edge-rusher Von Miller from their Week 1 opponent in free agency. Aiming to halt the Bills’ redemption trail and run back their success from a year ago will be a Rams outfit again led by Matthew Stafford and head coach Sean McVay. Odell Beckham Jr. – who suffered a torn ACL in the 23-20 Super Bowl victory – has been replaced by Allen Robinson. The former Bear will combine with league-leading receiver and Super Bowl MVP Cooper Kupp in forming a dangerous aerial threat, one that will be tested from the outset as they open the season against the league’s reigning number one defence.

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Los Angeles Rams vs Buffalo Bills Tip