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Los Angeles Chargers vs Kansas City Chiefs Tips, Odds & Predictions – NFL 2025

Arena Corinthians will play host to Saturday's Round 1 NFL game between Los Angeles Chargers and Kansas City Chiefs. The game kicks off at 10:00 am with Kansas City Chiefs heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Los Angeles Chargers vs. Kansas City Chiefs game and give you our free tips and bets.

When: Saturday September 6, 2025 at 10:00 am

Where: Arena Corinthians

Bet: Bet On This Match HERE

Los Angeles Chargers vs Kansas City Chiefs Odds

Los Angeles Chargers vs Kansas City Chiefs Preview

For the second straight season, the NFL is sending a Week 1 game down to Brazil with this AFC West clash between the Chargers and Chiefs set to light up the Neo Quimica Arena in Sao Paolo.

Kansas City won both head to head games last year by a combined margin of nine points and another close encounter will likely be on the cards here.

I’m not expecting a magical resurgence from a Chiefs offence that really struggled to move the ball last year, especially with an aging and depleted core of pass catchers.

Not to mention the Chargers preference to run as a first, second and third choice which might not be a recipe for a high scoring game, especially against the Chiefs imposing front.

Give me Kansas City (just) in a game where scoring drives will be few and far between and both running backs get a heavy workload.

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Head To Head Bet

Kansas City Chiefs
$1.57
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We're tipping Kansas City Chiefs to win at $1.57 odds.

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