SoFi Stadium will play host to Monday's Round 7 NFL game between Los Angeles Chargers and Indianapolis Colts. The game kicks off at 7:05 am with Los Angeles Chargers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Los Angeles Chargers vs. Indianapolis Colts game and give you our free tips and bets.
When: Monday October 20, 2025 at 7:05 am
Where: SoFi Stadium
Bet: Bet On This Match HERE
Los Angeles Chargers vs Indianapolis Colts Odds
Los Angeles Chargers vs Indianapolis Colts Preview
Indianapolis has a lot to gain from this game with a chance to show they are for real by navigating a west coast trip and upsetting the vulnerable Chargers.
LA has been decimated by injuries with the skeleton staff offensive line really struggling although they do deserve some credit for rallying late to knock off Miami last week.
But it is a different story against a team that might be a proper AFC contender in Indy.
The Chargers run defence has been gashed in the last three weeks Indianapolis has one of if not the best back in the league this season in Jonathan Taylor.
I think the Colts might be for real and love the value on offer for them here.
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Head To Head Bet
We're tipping Los Angeles Chargers to win at $1.75 odds.