Lucas Oil Stadium will play host to Monday's Round 4 NFL game between Indianapolis Colts and Tennessee Titans. The game kicks off at 4:00 am with Indianapolis Colts heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Indianapolis Colts vs. Tennessee Titans game and give you our free tips and bets.

When: Monday October 3, 2022 at 4:00 am

Where: Lucas Oil Stadium

Bet 💰: Bet On This Match HERE

Indianapolis Colts vs Tennessee Titans Odds

Indianapolis Colts vs Tennessee Titans Preview

It’s an AFC South showdown on Monday morning and these two teams have also underperformed so far this season.

These are two teams that rely very heavily on their Running Backs to produce and if that gets taken away, they struggle a lot.

The Colts have the 3rd best Run defence in the league (77 Yards Per Game) and the Titans have the 4th worst (145 Yards Per Game)

That stat alone is why I’m rolling with the Colts in this one.

They are $1.53 favourites but I think Jonathan Taylor is going to have an absolute field day against this defence.

Indianapolis Colts vs Tennessee Titans Tip