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Indianapolis Colts vs Denver Broncos Tips, Odds & Predictions – NFL 2025

Lucas Oil Stadium will play host to Monday's Round 2 NFL game between Indianapolis Colts and Denver Broncos. The game kicks off at 6:05 am with Denver Broncos heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Indianapolis Colts vs. Denver Broncos game and give you our free tips and bets.

When: Monday September 15, 2025 at 6:05 am

Where: Lucas Oil Stadium

Bet: Bet On This Match HERE

Indianapolis Colts vs Denver Broncos Odds

Indianapolis Colts vs Denver Broncos Preview

Was Daniel Jones a one hit wonder? We’re going to find out very quickly as he now has to play the Broncos who are a significantly better defence than the Dolphins.

The Broncos underperfermed last week and should theoretically improve from last weeks efforts.

I like the Broncos here and I think due to the tougher matchup, TE Tyler Warren sees a heap of receiver work.

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Head To Head Bet

Denver Broncos
$1.78
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We're tipping Denver Broncos to win at $1.78 odds.

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