Buffalo Bills vs San Francisco 49ers Tips, Odds & Predictions – NFL 2024

Highmark Stadium will play host to Monday's Round 13 NFL game between Buffalo Bills and San Francisco 49ers. The game kicks off at 12:20 pm with Buffalo Bills heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Buffalo Bills vs. San Francisco 49ers game and give you our free tips and bets.

When: Monday December 2, 2024 at 12:20 pm

Where: Highmark Stadium

Bet 💰: Bet On This Match HERE

Buffalo Bills vs San Francisco 49ers Odds

Buffalo Bills vs San Francisco 49ers Preview

It sure seems like Brock Purdy is going to miss another game for San Francisco with some real pessimism in the Bay Area about his availability for this one.

At publish, the market also looks like it is expecting Brandon Allen to get another start with the Bills short priced favourites at home.

Assuming that is the case, San Francisco won’t be able to do a whole lot of anything if last week is anything to go by, putting up just 10 points against Green Bay.

It does take some of the lustre off this game but with the Bills eager to keep pace with the Chiefs for the top seed in the AFC, they could be in the mood for a very big win taking advantage of their undermanned opponent.

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Buffalo Bills vs San Francisco 49ers Tip

Buffalo Bills
$1.32
Bet Now

We're tipping Buffalo Bills to win at $1.32 odds.

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