Highmark Stadium will play host to Monday's Round 1 NFL game between Buffalo Bills and Baltimore Ravens. The game kicks off at 10:20 am with Baltimore Ravens heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Buffalo Bills vs. Baltimore Ravens game and give you our free tips and bets.

When: Monday September 8, 2025 at 10:20 am

Where: Highmark Stadium

Bet 💰: Bet On This Match HERE

Buffalo Bills vs Baltimore Ravens Odds

Buffalo Bills vs Baltimore Ravens Preview

Less than eight months ago these two teams played out a postseason classic that was decided on a failed Ravens two point conversion.

This game is going to go down to the wire one way or another and despite this featuring two of the best quarterbacks, I’m leaning towards the running backs in this game.

Derrick Henry could score two on his own as he continues to win his fight against father time, but pairing him with James Cook makes this a far more appealing selection in this market.

Henry managed 19 touchdowns in the regular season and playoffs last year including in both Bills games while Cook lead the league with 16 in the regular season.

They should both be able to find the end zone in this primetime spectacular.

Content provided by Ladbrokes