State Farm Stadium will play host to Monday's Round 11 NFL game between Arizona Cardinals and San Francisco 49ers. The game kicks off at 8:05 am with San Francisco 49ers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Arizona Cardinals vs. San Francisco 49ers game and give you our free tips and bets.
When: Monday November 17, 2025 at 8:05 am
Where: State Farm Stadium
Bet 💰: Bet On This Match HERE
Arizona Cardinals vs San Francisco 49ers Odds
Arizona Cardinals vs San Francisco 49ers Preview
It really wont matter who is playing quarterback for either team in this game, its going to be a pretty comfortable 49ers win based on the respective efforts over the last few weeks.
The only way Arizonas offence looked good was against the hapless Cowboys and their job did not get any easier with the news Marvin Harrison Jr is out this week.
Admittedly their big loss in Seattle was their first defeat by more than four points all season but once San Francisco gets going its going to be over very quicky.
Only one point separated these teams in Week 3 but Im happy to back a comfortable margin for the visitors.
Content provided by Ladbrokes
Head To Head Bet
We're tipping San Francisco 49ers to win at $1.62 odds.
