Carlton’s Chris Judd and Sydney forward Adam Goodes are back in the AFL, while Collingwood midfielder Dane Swan appears to have proved his fitness.
Judd missed last week’s first win of the season with back tightness and will return against the Magpies at the MCG on Friday night.
Swan was wearing a moon boot earlier this week after suffering a sprained ankle in the Anzac Day win over Essendon.
Coach Nathan Buckley said they would not wait until Friday to decide on Swan’s availability.
The match will mark Mick Malthouse’s record 715th game as an AFL coach.
Goodes, the two-time Brownlow Medallist, has played in the reserves for the last two games.
Star first-year Swans player Isaac Heeney has an ankle injury and is among three omissions for Saturday’s home game against the Western Bulldogs.
Richmond have recalled Ty Vickery and Troy Chaplin among five changes for Saturday’s match against Geelong at the MCG.
But star utility Brett Deledio remains out of the side with a calf muscle injury.
The Cats have also lost star recruit Mitch Clark, who has a foot injury.
Brisbane dropped James Aish for the second time this season ahead of Saturday’s bottom-of-the-table match against Gold Coast.
Liam Shiels and Ryan Schoenmakers will come into Hawthorn’s side for the big Saturday night game against North Melbourne at Etihad Stadium.
They lost Brian Lake with a knee injury and left out Brendan Whitecross.
St Kilda captain Nick Riewoldt failed to prove his fitness as he recovers from a calf muscle injury.
But Essendon veteran Paul Chapman has a groin injury and is out of the side for Sunday’s game against the Saints.