Lucas Oil Stadium will play host to Monday's Round 6 NFL game between Indianapolis Colts and Arizona Cardinals. The game kicks off at 4:00 am with Indianapolis Colts heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Indianapolis Colts vs. Arizona Cardinals game and give you our free tips and bets.
When: Monday October 13, 2025 at 4:00 am
Where: Lucas Oil Stadium
Bet 💰: Bet On This Match HERE
Indianapolis Colts vs Arizona Cardinals Odds
Indianapolis Colts vs Arizona Cardinals Preview
Its 2003 all over again as you wonder if the Cardinals can keep up with the high powered Colts offence.
Indianapolis has beaten up on Miami, Tennessee and Las Vegas in three of their four wins this season and with the way Arizona is spiralling, this could be another one sided affair.
The Cardinals found not one, not two but three ways to fumble last weeks game to Tennessee and while there is the risk of an Arizona bounce back, its tough to have any confidence in them here.
Especially against a Colts team that has been scoring for fun, especially with the leagues leading rusher Jonathan Taylor coming off a three touchdown game.
Content provided by Ladbrokes
Head To Head Bet
We're tipping Indianapolis Colts to win at $1.24 odds.
