SoFi Stadium will play host to Monday's Round 2 NFL game between Los Angeles Rams and San Francisco 49ers. The game kicks off at 6:05 am with San Francisco 49ers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Los Angeles Rams vs. San Francisco 49ers game and give you our free tips and bets.

When: Monday September 18, 2023 at 6:05 am

Where: SoFi Stadium

Bet 💰: Bet On This Match HERE

Los Angeles Rams vs San Francisco 49ers Odds

Los Angeles Rams vs San Francisco 49ers Preview

It turns out that when you welcome back your healthy Super Bowl winning quarterback, your star defensive tackle looks rejuvenated and your head coach goes up against his bunny, it sets up for an encouraging result.

At least that’s what it was for the LA Rams last week as they roasted Seattle to pick up a first up win.

Unfortunately for them, Week 2 does not offer up the perfect setup with the 49ers dominating this rivalry and are coming off a 30-7 waxing of what many thought would be a half-decent Steelers team.

The 49ers have won the last eight regular season meetings between these teams and have handed the Rams some of their biggest defeats.

When Kyle Shanahan has his triplets fully healthy, Deebo Samuel, George Kittle and Chrisitan McCaffrey are damn near impossible to stop.

Even playing at SoFi isn’t going to give the Rams the help they need and I’ll happily jump on the 49ers to give LA a reality check.

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Los Angeles Rams vs San Francisco 49ers Tip