Samantha Stosur won’t be adding a second Family Circle Cup title to her collection after falling to Czech nemesis Lucie Safarova in the third round.

Stosur won the title in 2010 before making the French Open final two months later, but once again came unstuck against Safarova on Thursday.

The Australian’s 3-6 6-4 6-4 defeat was her ninth in 11 career meetings with the left-handed Safarova.

Canadian starlet Eugenie Bouchard admitted it was “a bit ugly” as she held off former world No.1 Venus Williams 7-6 (8-6) 2-6 6-4 to also reach quarter-finals.

Bouchard, an Australian Open semi-finalist who is seeded sixth in the green claycourt WTA premier level event, saved two set points in the first-set tiebreaker, and rallied from a break down in the third to advance to a meeting with second-seeded Serbian Jelena Jankovic.

Williams followed her younger sister, world No.1 and top seed Serena, out of the tournament.

“In the second set, she really started going for her shots,” Bouchard said.

“I just tried to keep fighting. It was a little bit ugly at times, but I just kept trying to fight through it.”

Jankovic defeated big-hitting Croatian Ajla Tomljanovic 7-5 6-1 to set up a meeting with Bouchard.

Tomljanovic, who had saved a match point in her first two matches this week, pushed Jankovic with a powerful baseline game in the opening set.

Trailing 5-3, the Croatian saved three set points before surrendering the opening set. From there, however, Jankovic cruised.

“My opponent was very aggressive today. That’s the way she plays,” Jankovic said. “I had to stay low and try to get my stride as well. I’m glad I was able to stay strong in that first set.”

Third-seeded Sara Errani of Italy advanced with a narrow 7-6 (8-6) 7-6 (7-5) victory over China’s Peng Shuai.

Peng had a set point in each set but couldn’t convert.

Errani will face Swiss qualifier Belinda Bencic, a 6-7 (4-7) 6-4 6-1 winner over Ukrainian Elina Svitolina in a battle of teenagers.

Fourth-seeded Sabine Lisicki was another third-round casualty, falling to fellow German Andrea Petkovic 6-1 6-0.

Petkovic next faces ninth-seeded Safarova.

Jana Cepelova followed up her big win over Serena Williams with a 7-6 (7-4) 3-6 6-3 victory over 13th-seeded Russian Elena Vesnina.

Cepelova will face fellow Slovakian Daniela Hantuchova in the quarter-finals. Hantuchova breezed past Teliana Pereira of Brazil 6-2 6-3