Injured star Maria Sharapova has withdrawn from the US Open because of a leg injury.

Sharapova has not played a match since losing to Serena Williams in the Wimbledon semifinals in July.

She withdrew from hard-court tournaments in Toronto and Cincinnati in August, citing a right leg strain.

Sharapova is a five-time major champion who was seeded No. 2 for the US Open, where play begins on Monday.

Lucky loser Daria Kasatkina will replace Sharapova in the main draw.

It’s the second time in three years that the 2006 champion has withdrawn from the year’s last Grand Slam event.