North Melbourne star Nick Dal Santo will miss about three months of this AFL season because of hamstring surgery.

The midfielder will have the operation on Thursday and is expected to be out of action for 10 to 12 weeks.

North sought advice this week on whether Dal Santo should rest or have surgery after he was hurt during last weekend’s win over Brisbane.

Daniel Wells (Achilles) and Scott Thompson (ankle) were also hurt during the Lions match, but the `Roos are hopeful the pair will play in Saturday night’s big home game against Port Adelaide, with teams to be named on Thursday.

Collingwood coach Nathan Buckley is also hopeful that captain Scott Pendlebury will come up for Friday night’s MCG match against St Kilda.

The star midfielder has a left ankle injury and left training early on Wednesday.

“He needs to know in his own mind that he’s right to go … he knows his body really well,” Collingwood coach Nathan Buckley said.

“He’s a professional in how he goes about it, so if he puts his hand up and ticks a few boxes from our side of things then he’ll play.”

The Magpies are having no luck with injuries – Ben Sinclair (hamstring) is definitely out of the side.

Taylor Adams (ankle) also appears unlikely to play, with the young onballer wearing a moon boot on his right foot at Wednesday’s training.

Adelaide defender Brodie Smith trained on Wednesday, but is no certainty to play in Saturday’s home match against Melbourne after suffering concussion last weekend.

Gold Coast will lose captain Gary Ablett because of his ongoing shoulder problems and Brisbane forward Michael Close is out for the rest of the season because of a knee reconstruction.

Essendon midfielder David Myers is out for about 12 weeks because of shoulder surgery.